Karyopharm Therapeutics: Promising Potential With 3 Ongoing Phase 3 Studies But Risky
wildpixel Thesis overview Karyopharm’s (NASDAQ:KPTI) lead candidate is selinexor, which has a novel mechanism of action. It acts as a selective inhibitor of nuclear export by binding to exporting 1 (XPO1). KPTI has been the leader in targeting this pathway and has successfully developed selinexor, with 3 approvals so far; in penta-refractory multiple myeloma, in…